The use of chiral coordination complexes as catalysts is referred to as enantioselective catalysis (or asymmetric catalysis). Typically, chiral ligands are used to make the catalysts chiral. Because most enantioselective catalysts are effective at low concentrations, they are well suited for industrial scale synthesis, as even exotic and expensive catalysts can be used at a reasonable cost. Enantioselective synthesis is an effective process in modern chemistry, especially in the field of medicines, because a molecule's distinct enantiomers or diastereomers often have varying biological activity.
Low substrate/catalyst ratios are effective for most enantioselective catalysts. They are often acceptable for industrial scale synthesis, even with expensive catalysts, due to their high efficiencies. Asymmetric hydrogenation, which is used to decrease a wide variety of functional groups, is an example of enantioselective synthesis.
- Chiral catalysts
- Chiral ligands for catalysis
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